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目的：观察拉西地平联合氯沙坦治疗老年性高血压的临床疗效。方法选择老年高血压患者110例,随机等分为对照组(采用氯沙坦单一药物治疗)、观察组(采用拉西地平联合氯沙坦治疗),8周后对两组患者相关指标进行分析比较。结果两组血压均有下降,对照组有效率78.2%,观察组有效率90.9%,观察组明显高于对照组,差异有统计学意义(P<0.01)。结论拉西地平联合氯沙坦是老年高血压患者的一种安全、有效、平稳的治疗方案。“,”Objective To evaluate the clinical efficacy of Lacidipine combined with Losartan on hypertension in the elderly.Methods One hundred ten cases of aged hypertension patients were selected and randomly divided into control group and experimental group. The fifty-five patients in control group were given Losartan only, while the other fifty-five patients in experimental group were given Lacidipine combined with Losartan.Analysis and comparison were made after eight weeks. Results Both two groups could effectively reduce hypertension,the response rates were 78.2% in control group and 90.9% in experimental group. The later was higher than the former. There was significant difference between the patients in two groups(P<0.01).Conclusion Lacidipine combined with Losartan proves an effective、safe and stable treatment for hypertension in the elderly.