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本文报道顺铂为主的联合化疗方案治疗晚期肺癌１６２例的近期疗效和毒性。非小细胞肺癌１４８例中ＣＡＰ方案７６例，有效率３７％；ＥＰ±Ｆ方案５ｌ例，有效率４１％；ＣＥ±Ｆ方案２１例。有效率１４％。小细胞肺癌１４中ＣＡＰ方案１例，达ＰＲ：ＥＰ方案８例，有效率７５％；ＥＰ方案５例，有效率１００％。毒性反应以血液学毒性、消化道反应较常见，多为Ⅰ°－Ⅱ°；多数有脱发，个别有一过性肝肾功能异常及ＥＣＧ改变。
This article reports the short-term efficacy and toxicity of cisplatin-based combination chemotherapy in the treatment of 162 patients with advanced lung cancer. Among 148 cases of non-small cell lung cancer, 76 cases had CAP regimen with a 37% effective rate; 51 cases had an EP±F regimen with 41% effective rate; 21 cases had a CE±F regimen. 14% efficient. In 14 cases of small cell lung cancer, there was 1 case of CAP regimen, 8 cases of PR: EP regimen, and 75% effective rate; 5 cases of EP regimen had 100% efficiency. The toxicity of hematological toxicity, digestive tract reaction is more common, mostly I ° - II °; most have hair loss, and one has a transient liver and kidney dysfunction and ECG changes.