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患者女,39岁.1992年7月7日因反复呃逆、泛酸伴上腹部疼痛不适来本院消化科就诊,经胃镜病理及胃液分析确诊为返流性胃炎,首次服用吗丁啉(西安杨森制药有限公司生产,批号:91卫药准字X一191号)10mg.每日3次,连续服用1个月始渐觉两侧乳房发胀,外观体积均匀增大,有少量乳汁自溢,并日趋加重,多至乳房胀痛难忍,需每天按摩数次,每日泌乳量最多达8～10ml.月经延期来潮.同年8月20日就诊于本院内分泌科:无头颅外伤及急慢性肝炎史.检两侧乳房似哺乳期形态,质感饱满,无结节包块,按压出乳汁少量.精神和神经无明显异常.头颅X线摄片:蝶鞍区无形态异常;子宫卵巢B超:子宫卵巢无形态异常.经血液内分泌检查:PRL7.16nmol/L(正常协定值<1.364nmol/L),黄体期LH/FSH=10.6/12.2mlu/ml(正常协定值
Patient female, aged 39. July 7, 1992 due to repeated hiccups, pantothenic acid with abdominal pain discomfort to our hospital digestive disease, gastroscopy and gastric juice was diagnosed as reflux gastritis, for the first time taking domperidone (Xi’an Janssen Pharmaceutical Co., Ltd. production, batch number: 91 health medicine quasi-word X a 191) 10mg. 3 times a day for 1 month before gradually began to feel both sides of the breast swollen, uniform appearance of the volume increases, a small amount of milk overflows, And increasingly heavier, up to the unbearable breast pain, massage several times a day, the daily amount of milk up to 8 ~ 10ml. Menstrual extension of the tide. August 20 the same year treatment of this hospital Endocrinology: no head trauma and acute and chronic History of hepatitis.Check both breasts lactation-like morphology, full texture, no nodules mass, press a small amount of milk.No obvious mental and nerve abnormalities .Craniotrope X-ray: the non-morphological abnormalities of the sella region; uterine ovarian B- No morphological abnormalities of uterine ovary.After the endocrine examination of blood: PRL7.16nmol / L (normal agreement value <1.364nmol / L), luteal phase LH / FSH = 10.6 / 12.2mlu / ml