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组织中存在能增殖、分化和自我更新的多能干细胞,氧化应激反应能诱导干细胞增殖,以满足组织的需求。文章简要分析了氧化应激反应刺激成体干细胞增殖可能的作用机制及其相关的信号通路。对深入了解干细胞的调节和组织功能紊乱的分子病因及进行干细胞治疗有重要的意义。
Tissue exists pluripotent stem cells that proliferate, differentiate, and self-renew. Oxidative stress induces stem cell proliferation to meet tissue needs. This article briefly analyzed the possible mechanism of oxidative stress stimulating the proliferation of adult stem cells and its related signaling pathways. It is of great significance to understand the molecular pathogenesis of stem cell regulation and tissue dysfunction and stem cell therapy.