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目的:分析乳腺导管内乳头状肿瘤术中冰冻病理的诊断价值。方法:随机选择于2011年3月至2016年3月间我院收治的术后石蜡病理诊断为乳腺导管内乳头状肿瘤患者200例,回顾性分析其临床资料,比较术后石蜡病理与术中冰冻病理结果,研究术中冰冻病理确诊的正确率以及诊断价值。结果:对于乳腺导管内乳头状肿瘤而言,术中冰冻病理的确诊正确率达到了88%,其中导管内乳头状癌确诊正确率为28.3%、导管内乳头状瘤确诊正确率为71.6%,数据对比差异显著(P<0.05);200例患者中,共有4例患者确诊病理等级提升,1例患者确诊病理等级降低,两组数据对比具有差异统计学意义(P<0.05)。结论:于乳腺导管内乳头状肿瘤患者而言,术中冰冻病理的意义非常重大,导管内乳头状癌的确诊正确率显著低于导管内乳头状瘤,伴发乳头溢液的病理确诊率显著高于未伴发乳头溢液的病理确诊率。
Objective: To analyze the diagnostic value of frozen pathology in intraductal papillary tumors. Methods: A total of 200 cases of intraductal papillary carcinoma were selected from March 2011 to March 2016 in our hospital. The clinical data of the patients were retrospectively analyzed. The postoperative paraffin pathology and intraoperative Frozen pathology results to study the accuracy of intraoperative pathological diagnosis of frozen and diagnostic value. Results: For intraductal papillary tumors, the accuracy rate of intraoperative frozen pathology was 88%. The accuracy rate of intraductal papillary carcinoma diagnosis was 28.3%, the accuracy of intraductal papilloma diagnosis was 71.6% There were significant differences between the two groups (P <0.05). Among the 200 patients, the pathological grade of 4 patients increased and the pathological grade of one patient decreased. There was statistically significant difference between the two groups (P <0.05). Conclusion: The intraoperative frozen pathology is of great significance in the diagnosis of intraductal papillary tumors. The diagnostic accuracy of intraductal papillary carcinoma is significantly lower than that of intraductal papillomas. The pathological diagnosis of nipple discharge with significant complications Higher than the unattached nipple discharge pathological diagnosis rate.