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在某一种族和社会中,绝经前妇女较其配偶具有预防冠状动脉粥样硬化能力,是因血浆脂蛋白胆固醇浓度,特别是高密度脂蛋白胆固醇(HDL-ch)男女有别,雌激素的“保护作用”,女性免于紧张、竞争及男性敌对行为的病理生理的影响。作者10年间对雌猴进行一系列试验,探讨粥样硬化与紧张、妊娠和甾体避孕药的关系。实验动物及方法:实验1:所用实验猴均用普通粥样硬化饮食喂养,测全部血清胆固醇,雌猴同于人类女性,HDL-ch高于雄性,冠状动脉粥样硬化较雄猴低两倍半,故选用Cynomolgus雌猴为实验动物。静脉苯巴比妥钠麻醉后尸检,用生理
In a race and society, premenopausal women have a greater ability to prevent coronary atherosclerosis than their spouses because of differences in plasma lipoprotein cholesterol levels, especially those of high-density lipoprotein cholesterol (HDL-ch), estrogen “Protecting”, women from the pathophysiology of tension, competition and male hostility. The author conducted a series of experiments on female monkeys in 10 years to explore the relationship between atherosclerosis and tension, pregnancy and steroid contraceptives. Experimental animals and methods: Experiment 1: All the experimental monkeys were fed with an ordinary atherosclerotic diet. All the serum cholesterol was measured. The females were the same as the human females. HDL-ch was higher than that of the males. Coronary atherosclerosis was twice as low as the male ones Half, so use the Cynomolgus female monkey as experimental animals. Intravenous phenobarbital anesthesia post-mortem, with physiology