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目的探讨舌体鳞癌前哨淋巴结(SLN)的检测及其对颈淋巴结转移的预测价值。方法用手术中注射蓝染料的方法,对21例未经治疗的舌体鳞癌颈淋巴结N0的患者手术中取SLN作快速冰冻病理检查,并与术后常规石蜡切片病理检查对照,观察冰冻病理检查前哨淋巴结转移与常规病理检查颈淋巴结转移的相关性及其对颈淋巴结转移癌的预测准确率。结果21例中15例成功地显示SLN,且全部集中在Ⅰ、Ⅱ、Ⅲ区,21例中6例出现颈淋巴结转移且均为SLN转移,SLN活检对颈淋巴结转移的阳性预测准确率为6/6。结论前哨淋巴结尤其是Ⅰ、Ⅱ、Ⅲ区淋巴结检测对判定舌体鳞癌CN0患者的颈淋巴结有否转移具有重要的预测价值。
Objective To investigate the detection of sentinel lymph node (SLN) in tongue squamous cell carcinoma and its predictive value for cervical lymph node metastasis. Methods In this study, 21 cases of untreated tongue squamous cell carcinoma of neck lymph node N0 were treated with SLN for rapid frozen pathological examination during surgery, and compared with routine paraffin section pathological examination after surgery to observe the pathological changes of frozen pathology To investigate the correlation between sentinel lymph node metastasis and cervical lymph node metastasis in routine pathological examination and its accuracy in predicting cervical lymph node metastasis. Results Of 21 cases, 15 cases showed SLN successfully, all of them were located in Ⅰ, Ⅱ and Ⅲ regions. Among 21 cases, 6 cases showed cervical lymph node metastasis and all had SLN metastasis. The positive predictive value of SLN biopsy for cervical lymph node metastasis was 6 / 6. Conclusion The detection of sentinel lymph nodes, especially Ⅰ, Ⅱ, Ⅲ regional lymph nodes detection of tongue squamous cell carcinoma of CN0 in patients with cervical lymph node metastasis has important predictive value.