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目的探讨Ⅰ、Ⅱ期中央区乳腺癌保乳治疗的可行性,研究手术切口的选择、术中操作技巧及乳房重塑方法。方法对31例肿瘤位于乳房中央区的Ⅰ～Ⅱ期原发性乳腺癌患者,行肿瘤局部扩大切除并乳房重塑及腋窝淋巴结清扫手术,其中2例切除乳头乳晕区。手术后常规给予化疗、放疗、内分泌及生物靶向治疗。结果全部患者成功施行保乳治疗后,经随访6～53个月(中位随访24个月),无局部复发。保乳治疗后对患侧乳房外观的评价:18例优秀,8例良好,5例一般,总体优良率为83.9%。结论位于中央区的Ⅰ、Ⅱ期原发性乳腺癌患者,只要规范治疗同样适合实施保乳,并可获得良好效果。
Objective To investigate the feasibility of breast-conserving breast cancer in the central area of stage Ⅰ and Ⅱ, and to study the choice of surgical incision, operative technique and breast remodeling. Methods Totally 31 patients with stage Ⅰ ~ Ⅱ primary breast cancer who were located in the central area of the breast were enrolled in this study. The tumors were locally expanded and resected, and breast remodeling and axillary lymph node dissection were performed. Among them, 2 patients underwent excision of the nipple wereola area. After surgery, conventional chemotherapy, radiotherapy, endocrine and biological targeting therapy. Results After successful breast-conserving treatment, all patients were followed up for 6 to 53 months (median follow-up 24 months) without local recurrence. After breast-conserving treatment of ipsilateral breast appearance evaluation: 18 cases were excellent, 8 cases were good, 5 cases were normal, the overall excellent rate was 83.9%. Conclusions Patients with stage I and II primary breast cancer in the central area may receive good results as long as standardized treatment is also suitable for breast-conserving.