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用放射免疫分析法，对３５例正常人和３０例手术前后的膀胱肿瘤患者尿中表皮生长因子（ＥＧＦ）含量为进行测定。结果：膀胱肿瘤患者术前ＥＧＦ含量为（２２．０６±１２．０５）μｇ／Ｌ，显著低于正常人群（３５．６９±２０．０８）μｇ／Ｌ（Ｐ＜０．０５），而膀胱肿瘤患者术后与正常人群相比，ＥＧＦ水平无显著差别。提示膀胱肿瘤无自分泌ＥＧＦ现象，尿中ＥＧＦ有促进肿瘤生长作用。
Radioimmunoassay was used to determine the content of epidermal growth factor (EGF) in urine of 35 normal subjects and 30 patients with bladder tumor before and after surgery. Results: The preoperative EGF content in bladder cancer patients was (22.06±12.05)μg/L, which was significantly lower than that in the normal population (35.69±20.08) μg/L (P<0.05). There was no significant difference in EGF levels between patients with tumors and normal controls. It is suggested that there is no autocrine EGF phenomenon in bladder tumors, and urinary EGF can promote tumor growth.