妊娠高血压综合症是产科常见并发症之一,多见于妊娠中晚期,临床表现为浮肿,高血压,蛋白尿三大症状,是危害母婴的一种严重综合症。以往我们传统用硫酸镁治疗该病,硫酸镁作用慢,疗效差,不安全,易出现镁中毒,在先兆子痫及子痫抢救中不够理想。近两年来,笔者采用硝普钠治疗妊娠高血压综合症,尤其在抢救先兆子痈及子痫中疗效显著。 妊娠高血压综合症的基本病理生理变化为血管痉孪,特别是全身细小动脉痉孪,使用扩血管药,特别是硝普钠具有扩张动静脉的双重作用,扩张动脉可除去基本病理因素,扩张静脉可防止心肾功能衰竭。重度妊高症使用硝普钠可快速有效稳妥解除动脉痉孪,控制高血压,防止子痫发生。硝普钠静滴后立即生效,停药后效应立即消失,剂量易掌握,一般成人剂量为12.5mg—25mg/次,8—400ng/min,滴速根据血压来调节,一般开始为10滴/min,渐增至30滴/min,勿过快,血压平稳后减速维持24—48小时,用药过程中密 Pregnancy-induced hypertension syndrome is one of the common complications of obstetrics, more common in late pregnancy, clinical manifestations of edema, hypertension, proteinuria three major symptoms, is a serious syndrome endangering mother and infant. In the past we used the traditional magnesium sulfate treatment of the disease, magnesium sulfate slow, poor efficacy, unsafe, prone to magnesium poisoning, pre-eclampsia and eclampsia rescue not ideal. The past two years, I used sodium nitroprusside treatment of pregnancy-induced hypertension, especially in the treatment of preeclampsia and eclampsia significant effect. The basic pathophysiological changes of pregnancy-induced hypertension syndrome are vasospasm, especially systemic arteriolar spasm. The use of vasodilator drugs, especially sodium nitroprusside, has dual effects of dilating arteries and veins. Arterial dilation can remove the basic pathological factors and expand Veins to prevent heart and kidney failure. Severe pregnancy hypertension using sodium nitroprusside can quickly and effectively relieve arterial spasm, control of hypertension, prevent eclampsia. Sodium nitroprusside immediately after taking effect immediately after stopping the effect immediately disappeared, easy to grasp the dose, the general adult dose of 12.5mg-25mg / time, 8-400ng / min, drip rate based on blood pressure to adjust, the general start of 10 drops / min, increasing to 30 drops / min, do not be too fast, slow down the blood pressure to maintain 24-48 hours, the drug process in the close