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目的探讨盐酸氨溴索联合头孢呋辛治疗小儿支气管肺炎的疗效及不良反应。方法选取从2011年10月至2012年10月在我院儿科进行住院治疗的120例小儿支气管肺炎患者作为研究对象,随机分成对照组与治疗组,各60人。对照组用常规止咳平喘、抗感染治疗的基础上加头孢呋辛进行治疗,治疗组在对照组治疗的基础上加用盐酸氨溴索进行治疗。观察治疗后两组患儿的治愈率和总有效率。结果治疗组治愈率为80%,总有效率为98%;对照组治愈率为55%;总有效率为85%,两组治愈率和总有效率的差异有统计学意义(P<0.05)。两组均未见明显不良反应。结论盐酸氨溴索联合头孢呋辛治疗小儿支气管肺炎疗效显著,未见明显的不良反应,值得临床推广。
Objective To investigate the efficacy and adverse reactions of ambroxol hydrochloride combined with cefuroxime in the treatment of bronchial pneumonia in children. Methods A total of 120 children with bronchopneumonia treated in our hospital from October 2011 to October 2012 were selected as study subjects and randomly divided into control group and treatment group with 60 patients each. The control group was treated with cefuroxime on the basis of conventional cough and asthma, anti-infective therapy. The treatment group was treated with ambroxol hydrochloride on the basis of the control group. Observe the cure rate and total effective rate of two groups after treatment. Results The cure rate was 80% and the total effective rate was 98% in the treatment group. The cure rate in the control group was 55% and the total effective rate was 85%. There was significant difference between the two groups in the cure rate and the total effective rate (P <0.05) . No obvious adverse reactions were found in both groups. Conclusion Ambroxol hydrochloride combined with cefuroxime axetil treatment of bronchial pneumonia in children significant effect, no significant adverse reactions, is worth clinical promotion.