作为免疫系统的核心组成部分,补体的生理作用主要是攻击外来病原和清除免疫复合物(IC)。在病理状态下,补体也会作用于自身组织,导致炎性反应和组织损伤。通过对动物模型的研究,人们发现在多种肾脏疾病包括与免疫有关的肾小球肾炎、肾移植后急慢性体液排斥和缺血再灌注损伤的发 As a central part of the immune system, the physiological role of complement is mainly to attack foreign pathogens and to clear immune complexes (ICs). In pathological conditions, complement also acts on its own tissues, leading to inflammatory reactions and tissue damage. Through the study of animal models, it was found that in a variety of kidney diseases including immune-related glomerulonephritis, acute and chronic renal transplant rejection of body fluids and ischemia-reperfusion injury