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目的:了解河南省嗜肺军团菌抗体在正常人群的分布及其规律。方法:每一调查对象采静脉血分离血清,用微量凝集试验测定嗜肺军团菌抗体,滴度≥1:16为阳性。同时填写统一调查表。结果:1～14血清型有三个未检出,分别是4、8、13型。在检出的11个血清型中以12型阳性率最高,6型次之;其阳性率分别为14.03%和10.45%。阳性者中最高抗体滴度为1:128,但大部分阳性者的抗体滴度低于1:128。123例抗体阳性者中有25.2%的人同时感染2个以上血清型。结论:健康人群中普遍存在嗜肺军团菌感染。且呈现多型性的特点,即在同一地区有许多血清型共存。人群中存在一定比例的重复感染。
Objective: To understand the distribution and regularity of Legionella pneumophila antibodies in normal population in Henan Province. Methods: Serum samples were collected from venous blood of each subject and antibodies against Legionella pneumophila were assayed by microagglutination test. The titer≥1: 16 was positive. At the same time fill in a unified questionnaire. Results: There were three undetected serotypes from 1 to 14, which were 4, 8 and 13 respectively. Among the 11 serogroups detected, the positive rate of type 12 was the highest, followed by that of type 6; the positive rates were 14.03% and 10.45% respectively. The titer of the highest antibody was 1: 128 in the positive group, but the antibody titer in most of the positive cases was less than 1: 128. 25.2% of the 123 antibody positive cases were infected with more than 2 serotypes at the same time. Conclusion: Legionella pneumophila infection is common in healthy people. And showing the characteristics of the type, that is, in the same area there are many serotypes coexist. There is a certain proportion of repeated infections in the population.