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目的:观察中药内服、外敷联合甲钴胺注射液治疗带状疱疹后遗神经痛的临床疗效。方法:将76例患者随机分为2组各38例,对照组给予甲钴胺静脉滴联合维生素B1口服治疗;治疗组在甲钴胺静脉滴的基础上联合芍药甘草汤内服、生山药捣烂外敷治疗,均治疗2周,采用疼痛视觉模拟评分(VAS)法对2组治疗前后神经痛的程度进行评分,并比较2组临床疗效。结果:总有效率治疗组为92.1%,对照组为74.4%,组间比较,差异有统计学意义(P<0.05)。治疗后2组疼痛VAS评分均较治疗前降低(P<0.05),治疗组VAS评分降低较对照组更显著(P<0.05)。结论:中药内服、外敷联合甲钴胺注射液治疗带状疱疹后遗神经痛疗效显著,值得临床推广应用。
Objective: To observe the clinical effect of traditional Chinese medicine orally and topical application of mecobalamin in the treatment of postherpetic neuralgia. Methods: 76 patients were randomly divided into 2 groups of 38 cases, the control group was given mecobalamin intravenous infusion of vitamin B1 oral treatment; the treatment group on the basis of mecobalamin intravenous infusion of peony licorice soup, raw yam smashed The patients were treated with external application for two weeks. The pain visual analogue scale (VAS) was used to evaluate the degree of neuralgia in the two groups before and after treatment. The clinical efficacy was compared between the two groups. Results: The total effective rate was 92.1% in the treatment group and 74.4% in the control group. There was significant difference between the two groups (P <0.05). The VAS score of the two groups after treatment was lower than that before treatment (P <0.05), while the VAS score of the treatment group was significantly lower than that of the control group (P <0.05). Conclusion: The efficacy of Herbal Oral Administration and topical combination mecobalamin in the treatment of postherpetic neuralgia is worthy of clinical application.