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目的探讨头孢硫脒联合氨溴索治疗小儿社区获得性肺炎的临床疗效。方法 118例社区获得性肺炎患儿随机分为两组各59例,均给予常规对症支持治疗,在此基础上对照组加用头孢唑啉、研究组加用头孢硫脒和氨溴索。结果研究组治疗总有效率明显高于对照组,痰培养转阴率明显高于对照组,差异有统计学意义(P<0.01)。结论氨溴索有助于降低头孢硫脒抗药性的影响,提高头孢硫脒的抗菌效果,可综合提高对小儿社区获得性肺炎的临床疗效。
Objective To investigate the clinical efficacy of cefathiamidine in combination with ambroxol in the treatment of infantile community-acquired pneumonia. Methods A total of 118 children with community-acquired pneumonia were randomly divided into two groups of 59 patients. All patients were given conventional symptomatic and supportive treatment. On the basis of this, cefazolin was added to the control group and cefathiamidine plus ambroxol in the study group. Results The total effective rate of the study group was significantly higher than that of the control group, and the negative conversion rate of sputum culture was significantly higher than that of the control group (P <0.01). Conclusion Ambroxol can reduce the impact of cefathiamidine resistance and improve the antibacterial effect of cefathiamidine, which can improve the clinical efficacy of community-acquired pneumonia in children.