The expansion of new structures in aggregation-induced emission/aggregation-induced emission enhancement(AIE/AIEE)systems has attracted persistent attention recently,from which more luminescent functional molecules with characteristic skeletons are derived to satisfy specialized applications.In this study,a series of derivatives cored by tetraphenyl enamine with various terminal groups were designed and synthesized based on a novel p-π conjugate chain structure(-C=C-N-).Experi-mental and theoretical studies reveal that attaching modified groups to enamine core is decisive to achieve successful conversion from non-luminance to AIEE-activity.Moreover,due to different substituent effect on electronic structure,molecular con-formation and molecular packing,diverse enamine compounds exhibited prominent substituent tunable emission properties,realizing regulated AIEE effect and multicolor emitting.These results not only offer a new method to design AIEgens/AIEEgens with p-π conjugate chain structures,but also provide in-depth knowledge for functional modifications of more novel AIE/AIEE units and materials.