OBJECTIVE:To evaluate the clinical effectiveness of Shumian capsule (舒眠胶囊) in improving the symptoms of insomnia,anxiety,depression,and other symptoms of convalescent patients of COV-ID-19.METHODS:Totally 200 patients were collected and randomly divided into experiment group (n =100)and control group (n =100).The control group was treated with Shumian capsule simulator,and the experiment group was treated with Shumian cap-sule.The improvement of TCM symptom score,the total effective rate and symptom disappearance rate of TCM symptoms in the two groups before and after treatment were observed,and the clinical effect was evaluated.RESULTS:One week after treatment,the scores of anxiety symptoms in the experiment group were significantly different from those in the control group (P ＜ 0.05),but there was no significant differ-ence in the scores of insomnia and depression be-tween the experiment group and the control group(P ＞ 0.05).There was no significant difference in the total effective rate and disappearance rate of TCM symptoms of insomnia,anxiety and depression be-tween the experiment group and the control group(P ＞ 0.05).After 2 weeks of treatment,the scores of insomnia,anxiety,depression and the total effec-tive rate of TCM symptoms in the experiment group were significantly different from those in the control group (P ＜ 0.05).There was no significant difference in the disappearance rate of insomnia,anxiety and depression between the experiment group and the control group (P ＞ 0.05).There were no significant differences in heart rate,respiration,systolic blood pressure and diastolic blood pres-sure between the experiment group and the con-trol group (P ＞ 0.05).CONCLUSION:Shumian capsule can significantly improve the symptoms of insomnia,anxiety and depression in COVlD-19\'s convalescent patients with sleep and mood disorders.