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目的调查2006年1月至2009年12月期间在南京市栖霞区妇幼保健院(原南京迈皋桥医院)就诊患者的梅毒感染发病情况,以为本地区该病的防治工作提供参考。方法查阅该院2006年至2009年共4年全年门诊、住院患者病历资料及实验室检测记录,将梅毒患者的相关信息录入Excel表,并进行相关统计分析。结果 2006年至2009年来共对6 988例患者进行了梅毒病原血清学[梅毒快速血浆反应素(RPR)和梅毒螺旋体明胶颗粒凝集实验(TPPA)]检测,确诊梅毒感染患者共149例,阳性率2.13%。其中男女比例为1∶1.87,女性患者构成比高于男性(65.10%vs 34.90%,P<0.01);一期梅毒44例,二期梅毒105例;主要分布科室为皮肤科、妇产科和泌尿外科;2006至2009年梅毒感染发现率呈逐年递升,分别为1.17%、1.93%、2.05%、3.04%,差异有统计学意义(χ2=8.98,P<0.01)。结论该院梅毒确诊病例逐年上升,梅毒的防控工作应该引起高度重视。
Objective To investigate the incidence of syphilis infection in patients from January 2006 to December 2009 in Qixia District Maternal and Child Health Hospital (Nanjing Maigaoqiao Hospital), in order to provide reference for the prevention and treatment of this disease in this area. Methods The hospital from 2006 to 2009, a total of 4 years outpatient and inpatient medical records and laboratory test records, the syphilis patient information into the Excel table, and related statistical analysis. Results A total of 6 988 patients were tested for syphilis seropositivity (syphilis RPR and TPPA) from 2006 to 2009. A total of 149 cases of syphilis infection were confirmed. The positive rate 2.13%. Among them, the ratio of male to female was 1: 1.87, the proportion of female patients was higher than that of male (65.10% vs 34.90%, P <0.01); 44 cases of primary syphilis and 105 cases of secondary syphilis; Urology. The incidence of syphilis infection in 2006-2009 increased year by year, accounting for 1.17%, 1.93%, 2.05% and 3.04%, respectively. The difference was statistically significant (χ2 = 8.98, P <0.01). Conclusions The confirmed cases of syphilis in this hospital are increasing year by year. The prevention and control of syphilis should be given high priority.