生物黏附性阴道片是一种新型的阴道给药方式。该制剂可长时间黏附于阴道黏膜表面,连续释药。局部给药后可促进药物在给药部位的吸收,避免肝首过作用和胃肠道的影响,提高生物利用度。随着新的生物黏附材料的不断开发应用,黏附材料稳定性和生物相溶性的不断提高,越来越多的局部使用药物被制备成生物黏附性阴道片。对近年来国内外生物黏附性阴道片的研究进展做相关阐述。 Bioadhesive vaginal tablets is a new vaginal administration. The preparation can adhere to the vaginal mucosal surface for a long time and release medicine continuously. After local administration can promote drug absorption at the site of administration, to avoid the first pass of liver and gastrointestinal effects, improve bioavailability. With the continuous development and application of new bioadhesive materials, the stability of adhesive materials and the increasing of biocompatibility, more and more topical medicines are prepared into bioadhesive vaginal tablets. In recent years, domestic and foreign bioadhesive vaginal tablets to do research on the progress made.