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目的观察2型糖尿病(T2DM)伴胸痛的患者冠心病(CAD)的疾病特点。方法以胸痛需行冠状动脉造影患者836例为研究对象,回顾性观察T2DM胸痛的患者CAD阳性率及CAD特点。结果 T2DM组140例,非T2DM患者(NT2DM组)696例。T2DM组冠心病阳性率明显高于NT2DM组(P<0.01)。T2DM组单支病变比NT2DM组明显少(P<0.01);双支病变比NT2DM组明显多(P<0.01);三支病变比NT2DM组明显多(P<0.01)。冠状动脉病变分布情况:左前降支病变T2DM组和NT2DM组无明显差别;右冠状动脉病变两组无明显差别;左回旋支病变两组无明显差别;左主干病变两组无明显差别。结论 T2DM伴胸痛的患者CAD发生率高,且双支病变和三支病变多。
Objective To investigate the characteristics of coronary heart disease (CAD) in patients with type 2 diabetes mellitus (T2DM) and chest pain. Methods Totally 836 cases of chest pain who underwent coronary angiography were selected as research objects. The positive rate of CAD and CAD features of patients with T2DM chest pain were retrospectively reviewed. Results There were 140 cases in T2DM group and 696 cases in non-T2DM group (NT2DM group). The positive rate of coronary heart disease in T2DM group was significantly higher than that in NT2DM group (P <0.01). The single vessel lesion in T2DM group was significantly less than that in NT2DM group (P <0.01). The double vessel lesion was significantly more than NT2DM group (P <0.01). The three vessel lesion was significantly more than NT2DM group (P <0.01). The distribution of coronary lesions: left anterior descending coronary artery lesions T2DM group and NT2DM group no significant difference; right coronary artery lesions no significant difference between the two groups; left circumflex artery lesions no significant difference between the two groups; left main trunk lesions no significant difference between the two groups. Conclusion The incidence of CAD in patients with T2DM with chest pain is high, and the incidence of double-vessel disease and three-vessel disease are higher.