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血清角蛋白19片段(CYRFRA21-1)是一种有效的肿瘤标志物。对肺癌中的非小细胞肺癌,特别是肺鳞癌诊断的敏感性和特异性显著高于其他肺癌相关肿瘤标志物。对可疑肺癌而无法获得病理诊断的患者,CYRFRA21-1有助于鉴别肺鳞癌和其他类型癌症;在肺癌患者的预后判断和转移检测方面,CYRFRA21-1也具有重要价值。
Serum keratin 19 fragment (CYRFRA21-1) is a potent tumor marker. The sensitivity and specificity of lung cancer diagnosis of non-small cell lung cancer, especially lung squamous cell carcinoma is significantly higher than other lung cancer-related tumor markers. CYRFRA21-1 is useful in differentiating squamous cell carcinoma from other types of cancer in patients with suspicious lung cancer who are not pathologically diagnosed. CYRFRA21-1 is also valuable in predicting prognosis and metastasis in patients with lung cancer.