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随着透析治疗、肾移植、饮食疗法等措施在慢性肾功能衰竭中的实施,患者寿命得以延长,这就有机会使尿毒症病人潜在的高脂血症的危害性表现出来。透析和肾移植虽可改善尿毒症的多种临床症候和体征,但高脂血症仍可延续,甚至透析本身以及肾移植中某些药物如皮质激素等的应用可进一步加重原先存在的脂质代谢紊乱。由于高脂血症与严重影响尿毒症预后的动脉粥样硬化及缺血性心脏病密切相关,因此已引起了人们对它的高度关注。晚近,不少学者发表了有关尿毒症、透析和肾移植中高脂血症变化规律及发病机理的研究,现归纳综述如下:
With dialysis, kidney transplantation, diet therapy and other measures in the implementation of chronic renal failure, patients with extended life expectancy, which gives the opportunity to uremia patients with potential dangers of hyperlipidemia manifested itself. Although dialysis and renal transplantation can improve a variety of clinical symptoms and signs of uremia, but hyperlipidemia can continue, and even dialysis itself and some drugs in kidney transplantation, such as corticosteroids and other applications can further aggravate pre-existing lipid Metabolic disorders. Because of its close relationship with atherosclerosis and ischemic heart disease, which seriously affect the prognosis of uremia, it has drawn great attention from people. Recently, many scholars published in the uremia, dialysis and renal transplantation in the law of change and pathogenesis of hyperlipidemia, are summarized as follows: