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目的对头孢地嗪治疗老年细菌性肺炎的安全性及有效性进行评价。方法回顾性分析100例老年细菌性肺炎患者简单随机化法随机分为对照组50例(头孢他啶治疗)、观察组50例(头孢地嗪治疗),进行统计、分析对照两组治疗前后白细胞水平变化、治疗后痰培养转阴时间、治愈率、显效率、有效率及不良反应发生率。结果两组治疗前白细胞差异无统计学意义(t=3.12,P>0.05);治疗后白细胞差异有统计学意义(t=5.12,P<0.05);两组治疗后痰培养转阴时间差异有统计学意义(t=4.77,P<0.05);治愈率、显效率、有效率及不良反应发生率比较差异有统计学意义(χ2=4.67、4.77、5.12、4.98,P<0.05)。结论头孢地嗪治疗老年细菌性肺炎具有安全、有效特点,较其他药物为优。
Objective To evaluate the safety and efficacy of cefodizime in the treatment of elderly bacterial pneumonia. Methods A retrospective analysis of 100 elderly patients with bacterial pneumonia simple randomization method were randomly divided into control group 50 cases (ceftazidime treatment), observation group 50 cases (cefodizime treatment), statistics, analysis of the control group before and after treatment leukocyte levels , Sputum culture after treatment negative conversion time, cure rate, markedly effective, effective and adverse reactions. Results There was no significant difference between the two groups before treatment (t = 3.12, P> 0.05). The difference of leukocytes after treatment was statistically significant (t = 5.12, P <0.05) Statistical significance (t = 4.77, P <0.05); The cure rate, effective rate, effective rate and the incidence of adverse reactions were significantly different (χ2 = 4.67,4.77,5.12,4.98, P <0.05). Conclusion Cefodizime is safe and effective in treating elderly bacterial pneumonia, which is superior to other drugs.