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目的观察比索洛尔治疗慢性心力衰竭的临床疗效。方法选择柳江县人民医院2008年1月至2011年2月收治的62例慢性充血性心力衰竭患者,随机分为观察组(32例)和对照组(30例),对照组给予常规抗心力衰竭治疗,观察组在常规治疗基础上加用比索洛尔,比较两组患者治疗前后临床症状、心功能改善及超声心动图变化等。结果观察组总有效率为90.6%,明显高于对照组的66.7%(P<0.05);两组经治疗后左室心功能及心率均明显改善(P<0.05),但观察组对左室射血分数(LVEF)及心率的改善明显优于对照组(P<0.05)。结论比索洛尔能显著改善慢性心力衰竭患者心功能并提高射血分数。
Objective To observe the clinical efficacy of bisoprolol in the treatment of chronic heart failure. Methods Sixty-two patients with chronic congestive heart failure admitted to Liujiang People’s Hospital from January 2008 to February 2011 were randomly divided into observation group (32 cases) and control group (30 cases). The control group was given routine anti-heart failure The treatment group and the observation group were given bisoprolol on the basis of conventional treatment. The clinical symptoms, cardiac function and echocardiographic changes before and after treatment were compared between the two groups. Results The total effective rate in the observation group was 90.6%, significantly higher than that in the control group (66.7%, P <0.05). Left ventricular function and heart rate were significantly improved in both groups (P <0.05) The ejection fraction (LVEF) and heart rate were significantly improved over the control group (P <0.05). Conclusion Bisoprolol can significantly improve cardiac function and increase ejection fraction in patients with chronic heart failure.