神经纤维瘤病是以多发性神经纤维瘤和皮肤色素斑为特征的遗传性疾病。自1882年 von Reckli-nghausen 阐明其本质以来,陆续发现病变累及人体多个系统和部位,临床表现多种多样。本病并非十分罕见,国内文献多属个案报导。本文就资料较完整的19例提出报告,并结合文献进行讨论。临床资料(附图)19例中男11例,女8例。初诊年龄最小者10岁,最大者55岁,平均28岁。有家族史记载的15例 Neurofibromatosis is a hereditary disease characterized by multiple neurofibromas and pigmented skin spots. Since von Reckli-nghausen elucidated its nature in 1882, it has been discovered that lesions affect multiple systems and sites in the human body, and their clinical manifestations are diverse. This disease is not very rare. Most domestic documents are case reports. This article presents a report on 19 cases with more complete information and discusses it with literature. Clinical data (drawings) 19 cases were 11 males and 8 females. The youngest young person was 10 years old, and the youngest was 55 years old, with an average of 28 years old. 15 cases with family history