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目的观察己酮可可碱(PTX)对外伤性脑梗死的治疗作用。方法选择外伤性脑梗死患者18例,除常规治疗外,治疗组加用己酮可可碱每天静脉滴注,对照组仅用常规治疗。比较两组的生存质量及磁共振波谱(MRS)测得的梗塞区域的代谢物质变化。结果治疗组恢复良好7例,中度残废5例;对照组恢复良好3例,中度残废2例。治疗组生存质量明显优于对照组。结论己酮可可碱对外伤性脑梗死有较好的治疗作用。
Objective To observe the therapeutic effect of pentoxifylline (PTX) on traumatic cerebral infarction. Methods 18 patients with traumatic cerebral infarction were selected. In addition to routine treatment, pentoxifylline was given daily to the treatment group, and the control group was given routine treatment only. The quality of life of the two groups and the change of metabolites in the infarct area measured by magnetic resonance spectroscopy (MRS) were compared. Results The treatment group recovered well in 7 cases, moderate disability in 5 cases; control group recovered in 3 cases, moderate disability in 2 cases. The quality of life in the treatment group was significantly better than that in the control group. Conclusion Pentoxifylline has a better therapeutic effect on traumatic cerebral infarction.