乳腺癌是女性恶性肿瘤中发病率最高的肿瘤。其临床结局变化很大,如何判断乳腺癌的预后已经成为各国学者所关注的问题。细胞增生活动和乳腺癌预后关系的研究已有不少报道。本文综述了近年来检测细胞增生的方法及其在乳腺癌预后研究方面的应用。 Breast cancer is the highest incidence of female malignant tumors. The clinical outcome has changed greatly. How to judge the prognosis of breast cancer has become a concern among scholars from various countries. There have been many reports on the relationship between cell proliferation activity and prognosis of breast cancer. This article reviews the methods of detecting cell proliferation in recent years and its application in the study of prognosis of breast cancer.