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丹那唑是一种17a乙炔睾丸酮的2·3异噻唑衍化物,连续应用在猴和人类可以抑制排卵。近来实验证明除了它的抗促性腺激素和弱雄激素作用外,还有孕酮类活性。据资料证明孕酮类制剂,可以溶解黄体所以在4名正常妇女黄体期给予丹那唑,以确定有无溶解黄体作用。 4名受试者首先记录基础体温一周期以上,在随后的第一周期(对照周期)记录基础体温及每天服用安慰剂,并在周期第十天起一直到月经来潮时,
Danazol is a 2,3-isothiazole derivative of 17a acetylene testosterone, which can be used to inhibit ovulation in monkeys and humans. Recently experiments show that in addition to its anti-gonadal and androgenic androgenic effects, there are progesterone activity. According to data progesterone preparations, you can dissolve the corpus luteum during the so-luteal phase in four normal women given to determine whether the role of dissolution of corpus luteum. Four subjects first recorded basal body temperature more than one cycle, recorded basal body temperature in the first cycle (control cycle) and placebo daily, and from the tenth day of the cycle until menstruation,