论文部分内容阅读
目的研究≤45岁青年脑卒中患者与Lp（a）水平的相互关系。方法用ELISA双抗体夹心法测定≤45岁青年脑卒中组、＞45岁脑卒中组和对照组的血清Lp（a）水平。结果≤45岁年青脑卒中组血清Lp（a）升高率（40．91％）和平均水平（35．59±19．06）明显高于＞45岁脑卒中组（P＜0．01）；≤45岁年轻脑卒中级血清Lp（p）的OR值，明显高于＞45岁脑卒中组（P《＜0．05）。脑梗死组血清LP（a）升高率．和平均水平与脑出血组无显著性差异（P＞0．05）。LP（a）与血纤维蛋白原水平存在正相关（r＝0．234，P＜0．01），而与其它脑血管病的危险因素无关（P＞0．05）。结论血清Lp（a）水平升高是≤45岁年轻脑梗死患者独立的危险因素。
Objective To investigate the correlation between the level of Lp (a) and stroke in 45-year-old young stroke patients. Methods Serum Lp (a) levels were measured by sandwich enzyme-linked immunosorbent assay (ELISA) in young stroke patients younger than 45 years, stroke patients aged> 45 years, and control group. Results The serum Lp (a) elevation rate (40.91%) and the average level (35.59 ± 19.06) in the stroke group younger than 45 years old were significantly higher than those in the stroke group> 45 years old (P <0.01) ; The OR of serum Lp (p) in younger stroke younger than 45 years old was significantly higher than that of stroke group> 45 years old (P <0.05). Serum LP (a) increased rate in cerebral infarction group. And the average level of cerebral hemorrhage group no significant difference (P> 0.05). There was a positive correlation between LP (a) and fibrinogen level (r = 0.234, P <0.01), but not with risk factors of other cerebrovascular diseases (P> 0.05). Conclusion The elevated serum Lp (a) level is an independent risk factor for patients younger than 45 years old with cerebral infarction.