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呋喃丙胺顺式异构体的合成,系按文献方法制备顺式β-(5-硝基-2-呋喃)-丙烯酸,然后于低温下与异丙胺经混合酸酐法,氨化为顺式与反式两种酰胺的混合物,再经分离获得顺式异构体。实验动物药理结果证明其生物活性与反式异构体相似。
The synthesis of cis-isomer of furanpropylamine is based on the literature method for the preparation of cis- (5-nitro-2-furan) -acrylic acid followed by mixed anhydride method with isopropylamine at low temperature, Trans mixture of two amides, and then separated to obtain cis-isomers. Laboratory animal pharmacological results show that its biological activity and trans-isomers.