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中枢神经系统感染可并发严重脑水肿,脑水肿则常是致死和致残的重要因素.颅内压(ICP)增加常妨碍脑血流量(CBF),而引起中枢神经损害,并使脑灌注压(CPP)降低致脑缺血.本文研究了17例患严重中枢神经系统感染、处于深昏迷(格氏评分法<7分),年龄在45天到11岁的患儿脑灌注压.17例中有11例脑膜炎(64.7%),5例(29.4%)脑炎.13例作硬膜下插管.4例行脑室插管作连续颅内压监护.紧急情况时每小时对患儿的平均动脉压,颅内压及脑灌注压计算报告一次.脑灌注压是用平均动脉压减去此时最大颅内压来计算.存活组11例(64.7%)患儿与死亡组6例
Central nervous system infection may be accompanied by severe cerebral edema, brain edema is often an important factor in lethal and disabling .Impression of intracranial pressure (ICP) often impedes cerebral blood flow (CBF), causing central nervous system damage and cerebral perfusion pressure (CPP) to reduce cerebral ischemia.We studied the cerebral perfusion pressure in 17 children with severe central nervous system infection who were in deep coma (Gersch score <7), aged 45 days to 11 years old. 11 cases of meningitis (64.7%), 5 cases (29.4%) of encephalitis, 13 cases of subdural intubation, 4 cases of intraventricular intubation for continuous monitoring of intracranial pressure.Every hour in emergency cases of children The average arterial pressure, intracranial pressure and cerebral perfusion pressure calculation report once.The cerebral perfusion pressure is the mean arterial pressure minus the maximum intracranial pressure at this time to calculate the survival group of 11 patients (64.7%) and death group of 6 patients