筛选镇痛药时采用的致痛方法,概括起来有物理性刺激法和化学性刺激法。已有的测痛方法多数需将动物固定,对评定镇痛药效价会带来一定的影响。有报道,在大鼠或猫的前足爪背部皮下注射甲醛致痛模型的优点是动物 Screening analgesics used in the pain method, summed up the physical stimulation and chemical stimulation. The majority of existing methods of measuring pain need to be fixed on the animal, which will have a certain impact on the evaluation of the analgesic potency. It has been reported that the advantage of injecting formalin pain models subcutaneously in the back of the forefoot of rats or cats is the animal