目的了解泰素和放射对人盲肠未分化腺癌细胞系（Ｈｃｅ８６９３）的联合作用效应。材料与方法应用ＭＴＴ比色法，细胞核分裂指数，ＤＮＡ琼脂糖电泳及流式细胞仪检测技术。结果泰素对该细胞的抑制呈一定的剂量依赖性；低浓度的泰素（１０μｇ／ｍｌ）可致分裂细胞明显增加；单纯泰素（２０μｇ／ｍｌ）和单纯放射作用后的１８小时均产生细胞凋亡现象，而细胞经泰素联合放射作用后的３～２４小时均出现了ＤＮＡ梯状（Ｌａｄｄｅｒ）条带及凋亡（Ａｐｏｐｔｏｓｉｓ）小峰。结论泰素结合放射有一定协同作用，至少有相加效应。 Objective To understand the combined effects of paclitaxel and radiation on human cecal undifferentiated adenocarcinoma cell line (Hce8693). Materials and methods MTT colorimetry, nuclear index, DNA agarose electrophoresis and flow cytometry were used. Results Taxol had a dose-dependent inhibitory effect on the cells; low concentrations of Taxol (10 μg/ml) significantly increased the number of dividing cells, and simple Taxol (20 μg/ml) and 18 hours after irradiation alone produced Apoptosis was observed in cells, but ladders and apoptosis peaks appeared in 3 to 24 hours after cells were treated with taxol and combined radiation. Conclusions TAX combined with radiation has a certain synergistic effect, at least with additive effects.