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丙酮酸激酶(pyruvate kinase,PK)为红细胞无氧糖酵解中三个限速酶之一。PK缺乏为该代谢途径中引起遗传性非球形细胞性溶血性贫血的一种重要酶缺乏,且同多种血液病有关,
Pyruvate kinase (PK) is one of the three rate-limiting enzymes in erythrocyte anaerobic glycolysis. PK deficiency is a major enzyme deficiency in this metabolic pathway that causes hereditary non-spherical hemolytic anemia and is associated with a variety of blood diseases,