论文部分内容阅读
近来逐渐阐明原发癌灶的局部免疫是防止结肠癌肝转移的第一道防御机制,极为重要。本文研究结肠癌前列腺素E_2(PGE_2)与局部免疫功能的关系,以明确局部免疫功能与肝转移的关系。对象:进展期结肠癌48例,其中手术时有肝转移者14例,无肝转移者32例,8例胆石症作为对照组。各组间统计学上无年龄性别差异。方法:取末稍血、灌流肿瘤动静脉血,测PGE_2和CEA值,以及作单核细胞培养测上清液中PGE_2浓度。
Recently, it has become increasingly important to elucidate that the local immunity of the primary cancer foci is the first defense mechanism to prevent the liver metastasis of colon cancer. This article studies the relationship between PGE 2 and local immune function in colon cancer to clarify the relationship between local immune function and liver metastasis. PARTICIPANTS: Forty-eight patients with advanced colon cancer, including 14 patients with liver metastasis during surgery, 32 patients without liver metastases, and 8 patients with cholelithiasis as a control group. There was no statistical difference in age and sex between the groups. Methods: The blood and arterial venous blood of the tumor were perfused, the PGE 2 and CEA values were measured, and the concentration of PGE 2 in the supernatant was determined by monocyte culture.