1912年Stillman第1次描述了嗜酸细胞增多症的临床征象。以后发现许多原因可导致嗜酸细胞增多(持续>5×10~9/L),如过敏、寄生虫病、严重细菌感染、血液病、肿瘤、血管炎及某些自身免疫性疾病等。这些患者多具有共同并发症,可累及1个或多个脏器,并出现相应症状和体征。由于所累及脏器多样性,其临床表现十分错综复杂,历史上曾有不少命名,如嗜酸细胞白血病、弥散性嗜酸细胞 Stillman first described the clinical signs of eosinophilia in 1912. Later found that many reasons can lead to eosinophilia (continued> 5 × 10 ~ 9 / L), such as allergies, parasitic diseases, serious bacterial infections, blood diseases, tumors, vasculitis and some autoimmune diseases. These patients have more common complications, can affect one or more organs, and the corresponding symptoms and signs. Due to the diversity of organs involved, its clinical manifestations are very complicated, there have been many names in history, such as eosinophilic leukemia, diffuse eosinophils