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作者等检查了临床表现为肾上腺皮质机能亢进的肾上腺皮质增生4例及腺瘤1例。本文仅涉及引起柯兴氏综合症的病变,讨论肾上腺皮质的超微结构改变与光镜病变的联系,并试图探讨肾上腺皮质超微结构上的某些联系,希望得出从肾上腺皮质细胞的超微结构对肾上腺皮质内分泌机能状态的估计,以弥补光镜在这一方面的不足,尤其对在光镜下看不出显著病变的病例。材料与方法 5例患者均为女性。年令最小11岁,最大35岁。发病最短9个月,最长为6年。肾上腺重量除一例为皮质腺瘤外,分别为2、5.5、5.8及10克。
The authors examined 4 cases of adrenocortical hyperplasia and 1 case of adenoma with clinical manifestations of adrenocortical hyperactivity. This article deals only with lesions that cause Cushing’s syndrome, discusses the association of ultrastructural changes in the adrenal cortex with lesions of light microscopy, and attempts to investigate certain links in the ultrastructure of the adrenal cortex, hoping to derive supercells from adrenocortical cells. The microstructural assessment of adrenocortical endocrine function states compensates for the lack of light microscopy in this area, especially in cases where significant lesions are not seen under light microscopy. Materials and Methods Five patients were female. The minimum age is 11 years and the maximum is 35 years old. The shortest onset is 9 months and the longest is 6 years. Adrenal weights were 2, 5.5, 5.8, and 10 grams, except for one case of cortical adenomas.