基于吲哚衍生物和氮杂环衍生物的抗真菌活性 ,设计合成了含有噻二唑、三氮唑、二唑等氮杂环及其相应开链硫脲结构的吲哚衍生物和吲哚希夫碱化合物共 18个 ,除化合物 2、3和 16外其余目标物未见报道 ,其结构经1H NMR、IR和MS确证 ,体外抑菌实验正在进行 Based on the antifungal activity of indole derivatives and azole derivatives, the indole derivatives containing thiadiazoles, triazoles, oxadiazoles and their corresponding open-chain thioureas and indole derivatives were designed and synthesized There were 18 compounds of dichloro-Schiff base, and the other compounds except compounds 2, 3 and 16 were not reported. Their structures were confirmed by 1H NMR, IR and MS. Antibacterial experiments in vitro were underway