论文部分内容阅读
用连续灌注导管测压，并测定胃液和血清的表皮生长因子（ＥＧＦ）的含量，为了解十二指肠球溃疡（ＤＵ）患者消化间期移行性复合运动（ＭＭＣ）的规律，及其胃液和血清中的表皮生长因子含量的变化。结果显示：１、６０％ＤＵ患者缺乏ＭＭＣⅢ期，与正常人比Ｐ＜０．０５。２、ＤＵ患者ＭＭＣⅢ期持续时间（２．９±１．９ｍｉｎ）比正常人（４．３±１．１ｍｉｎ）缩短，（Ｐ＜０．０５）。３、ＤＵ患者ＭＭＣⅢ用十二指肠近端及远端的运动波幅较正常人减低（Ｐ＜０．０１）。４、ＤＵ患者的胃液和血清的表皮生长因子含量显著降低，分别为１９９．２７±１４７．８１ｐｇ／ｍＬ和１４８．６７±１２４．３１ｐｇ／ｍＬ，（Ｐ＜０．０１）。说明消化间期移行性复合运动和表皮生长因子在十二指肠球溃疡发病机理上起一定作用。
Continuous perfusion catheter manometry, and determination of gastric juice and serum epidermal growth factor (EGF) content, in order to understand the duodenal ulcer (DU) in patients with interplastic migration syndrome (MMC) of the law, and its gastric juice And serum levels of epidermal growth factor. The results showed that 1,60% DU patients lack MMCⅢphase, P <0.05.2 compared with normal people, MMC duration of DU patients (2.9 ± 1.9min) was higher than that of normal people (4.3 ± 1) 1 min), (P <0.05). 3, DU patients MMCⅢ proximal and distal duodenal exercise amplitude decreased compared with normal (P <0.01). The content of epidermal growth factor in gastric juice and serum of DU patients were significantly decreased, which were 199.27 ± 147.81pg / mL and 148.67 ± 124.31pg / mL, respectively (P <0.01). Indicating that interim gastrointestinal migrating complex movement and epidermal growth factor play a role in the pathogenesis of duodenal ulcer.