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目的探讨痛风性关节炎与高血压、高脂血症、脂肪肝、糖尿病等伴发病的关系,及与饮食、疲劳、季节、遗传等因素的关系。方法本文收集了208例痛风病人,从性别、年龄、体重、病程、诱发因素、好发部位、好发季节、急性发作的间歇期、伴发病及家族遗传史、血尿酸水平等方面进行临床观察。结果痛风性关节炎病人中伴发高血压占68.75%,高血脂占53.37%,有家族史占21.15%;由高嘌呤饮食诱发占65.87%,疲劳诱发占32.21%;以第一跖趾关节好发的占42.79%。痛风病人的体重指数与血尿酸水平呈正相关(P<0.05)。结论痛风性关节炎的发作与饮食、气候、疲劳因素等有相关性;往往与高血压、高血脂、糖尿病等代谢性疾病并发;有明显的家族遗传性;好发于下肢小关节,以第一跖趾关节最多见。
Objective To investigate the relationship between gouty arthritis and the complication of hypertension, hyperlipidemia, fatty liver and diabetes and its relationship with diet, fatigue, seasons and heredity. Methods A total of 208 cases of gout patients were collected from the aspects of sex, age, body weight, course of disease, predisposing factors, predilection sites, incidence of seasons, intermittent episodes of acute exacerbations, concomitant onset and family history, serum uric acid levels . Results Gouty patients with hypertension accounted for 68.75%, hyperlipidemia accounted for 53.37%, family history accounted for 21.15%; induced by high purine diet accounted for 65.87%, fatigue induced accounted for 32.21%; with the first metatarsophalangeal joint good Hair accounted for 42.79%. Body mass index of gout patients and serum uric acid levels were positively correlated (P <0.05). Conclusions The onset of gouty arthritis is related to diet, climate and fatigue factors. It is often associated with metabolic diseases such as hypertension, hyperlipidemia and diabetes mellitus. There is obvious familial heredity. It develops in lower limbs and joints, A metatarsophalangeal joints see the most.