在未经手术的活动性或慢性十二指肠溃疡(DU)患者中,合并胃癌被认为是罕见的。本文报道2例有长期DU病史的胃癌,并就文献中236例进行临床分析。男女各一,年龄分别为64和51岁,有10和19年十二指肠溃疡病史。均有十二指肠溃疡较典型的上腹痛,用抗酸剂可缓解。在入院前都曾作过4次胃肠道钡剂造影。例1,4次钡剂检查均示十二指肠溃疡、变形、疤痕组织形成,但无活动性溃疡可见。服用甲氰咪胍后症状 In patients with unoperated active or chronic duodenal ulcer (DU), gastric cancer is considered rare. This article reports 2 cases of gastric cancer with a long history of DU, and conducted clinical analysis of 236 cases in the literature. One male and one male, ages 64 and 51 years old, with a history of duodenal ulcers in 10 and 19 years. Duodenal ulcers are more typical abdominal pain, with antacids can be alleviated. Prior to admission, he had had 4 times of gastrointestinal barium angiography. In Example 1, 4 times of barium examination showed duodenal ulcer, deformation, scar tissue formation, but no active ulcer was visible. After taking cimetidine