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20世纪 90年代以来 ,甲氨喋呤 (ＭＴＸ)对类风湿性关节炎 (ＲＡ)的疗效已受到国内外学者的广泛肯定[1 ] ,抗疟药治疗ＲＡ目前也逐渐受到重视 ,抗疟药不但与ＭＴＸ有协同作用 ,而且可以降低后者的肝毒性[2 ] ,ＭＴＸ加羟氯喹 (ＨＣＱ)已成为目前国内外治疗ＲＡ常用的联合治疗方
The efficacy of methotrexate (MTX) on rheumatoid arthritis (RA) has been widely acknowledged by scholars at home and abroad since the 1990s [1]. At present, the treatment of RA with anti-malarial drugs is gradually being emphasized. Antimalarial drugs Not only with MTX synergies, but also reduce the latter liver toxicity [2], MTX plus hydroxychloroquine (HCQ) has become the treatment of RA commonly used at home and abroad