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目的探讨宫腔镜电切术治疗慢性宫颈炎的临床疗效以及对患者血清炎症因子的影响,以期为临床治疗提供理论依据。方法将2011年2月~2013年2月间收治的120例慢性宫颈炎患者,随机分为实验组与对照组,每组60例。实验组患者给予宫腔镜电切术治疗;对照组给予激光术治疗。比较术后两组患者临床疗效、并发症发生率以及血清白介素-6(IL-6)、高敏C反应蛋白(hs-CRF)、肿瘤坏死因子(TNF-α)以及超氧化物歧化酶(SOD)水平。结果经治疗后,实验组患者的临床总有效率为91.7%,并发症发生率为10.0%;而对照组则为76.7%、30.0%,两组比较差异有统计学意义(P<0.05);实验组患者的IL-6、hs-CRF、TNF-α以及SOD分别为(31.91±5.18)pg/m L、(1.29±0.25)mg/m L、(0.62±0.15)ng/m L、(302.33±32.20)ng/m L;而对照组分别为(48.85±5.54)pg/m L、(1.92±0.21)mg/m L、(1.09±0.17)ng/m L、(385.03±20.94)ng/m L,两组比较,实验组各项指标均显著低于对照组(P<0.05)。结论宫腔镜下电切术治疗慢性宫颈炎临床疗效显著,能够显著降低患者血清炎症因子水平,并发症发生率较少,值得进行临床推广。
Objective To investigate the clinical efficacy of hysteroscopic resection of chronic cervicitis and serum inflammatory factors in order to provide a theoretical basis for clinical treatment. Methods A total of 120 patients with chronic cervicitis admitted from February 2011 to February 2013 were randomly divided into experimental group and control group, with 60 cases in each group. Patients in the experimental group were given hysteroscopic resection and the control group received laser treatment. The clinical efficacy, the incidence of complications and the levels of serum interleukin-6, hs-CRF, TNF-α and superoxide dismutase (SOD) were compared between the two groups. )Level. Results After treatment, the total clinical effective rate was 91.7% and the complication rate was 10.0% in the experimental group compared with 76.7% and 30.0% in the control group. The difference between the two groups was statistically significant (P <0.05). The levels of IL-6, hs-CRF, TNF-α and SOD in the experimental group were (31.91 ± 5.18) pg / m L, 1.29 ± 0.25 mg / m L and 0.62 ± 0.15 ng / 302.33 ± 32.20 ng / m L, while the control group were (48.85 ± 5.54) pg / m L, 1.92 ± 0.21 mg / m L, 1.09 ± 0.17 ng / m L and 385.03 ± 20.94 ng / / m L, the two groups, the experimental group indicators were significantly lower than the control group (P <0.05). Conclusion The hysteroscopic resection of chronic cervicitis has obvious clinical curative effect, can significantly reduce the level of serum inflammatory cytokines, and the incidence of complications is less, so it is worth to carry out clinical promotion.