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胃癌为常见的恶性肿瘤。对胃癌的组织发生,仍有某些不同的观点,一些学者认为肠型胃癌由胃粘膜化生的肠上皮癌变而来,而多数学者则认为胃癌一般原发于胃粘膜腺颈部的上皮,此处细胞具有潜在的多方向分化的增殖能力,在致癌因素作用下这些细胞可增生、间变和癌变,而在增生癌变过程中,向肠上皮方向分化时即形成肠型胃肠 向胃型上皮方向分化时即形成胃型胃癌;同时向肠型上皮和胃型上皮分化时即形成混合型胃癌,同时干细胞在异常分化过程中,还可以形成中间型上皮,即增生的同一细胞具有产生二种粘液的功能,由此种中间型上皮发生的癌也属于混合型胃癌。我们应用Alciau blue-PAS染液的组织化学染色,观察100例胃癌的组织发生学类型,并
Gastric cancer is a common malignancy. There are still some different opinions on the carcinogenesis of gastric cancer. Some scholars believe that intestinal type gastric cancer is caused by intestinal epithelial carcinogenesis from gastric mucosal metaplasia, and most scholars believe that gastric cancer is generally primary in the epithelium of the glands of the gastric mucosa. Here, the cells have the potential for multi-directional differentiation and proliferative capacity. Under the action of carcinogenic factors, these cells can proliferate, metastasize and become cancerous. In the process of proliferative carcinogenesis, when they differentiate toward the epithelium of the intestine, they form the intestinal type gastrointestinal to stomach type. Gastric cancer is formed when epithelial direction differentiates; mixed gastric cancer is formed when it differentiates into intestinal epithelium and gastric epithelial, and in the process of abnormal differentiation of stem cells, intermediate epithelium can also be formed, ie, the same cell with proliferation has two The function of the mucus, the cancer that arises from this type of intermediate epithelium also belongs to the mixed gastric cancer. We used Histochemical staining of Alciau blue-PAS staining fluid to observe the histogenetic types of 100 cases of gastric cancer, and