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高粘度症候群是由于血液粘度增加所引起的神经功能障碍、视力障碍和出血倾向的综合症状。作者鉴于细胞压积是影响血液粘度最重要的因素,而且已从真性红细胞增多症证实异常的血液粘度引起症状,认为白血病患者大量增加的白细胞也许会诱发高粘度症候群。作者观察了3例慢淋白血病和3例骨髓性白血病,这些患者均有高粘度症候群的临床症状(包括深度的嗜睡、步态不稳、视力障碍和昏迷等)。用 Wells-Brookfield 徼粘度计在23S~(-1)和230S~(-1)两个切变率下测定所有病人的全血粘度。23S~(-1)
High-viscosity syndrome is a syndrome of neurological dysfunction, visual impairment and bleeding tendency due to increased blood viscosity. AUTHOR Because cytostatics are the most important factor affecting blood viscosity and have caused symptoms from abnormal blood viscosity in polycythemia vera, the increased presence of white blood cells in patients with leukemia may induce hyperviscosity syndrome. The authors looked at 3 cases of chronic leukemia and 3 cases of myeloid leukemia, all of whom had clinical symptoms of high-viscosity syndrome (including deep lethargy, gait instability, visual impairment and coma). All patients were tested for their whole blood viscosity using a Wells-Brookfield viscometer at both 23S-1 and 230S-1 shear rates. 23S ~ (-1)