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目的探讨肝硬化腹水患者不同血清钠水平与病情严重程度的关系。方法回顾分析2008年7月-2010年6月收治47例肝硬化腹水并发低钠血症患者,根据其入院时血清钠水平分为低钠血症轻(A组)、中(B组)、重(C组)3组。比较肝硬化腹水患者不同血钠水平的腹水程度及疗效的关系、以及低钠程度与肝性脑病、肝肾综合征和死亡发生率的关系。结果与A组比较,B、C两组腹水量、肝性脑病、肝肾综合征及病死率明显增高,差异有统计学意义(P<0.05);对治疗的效果明显降低(P<0.05)。结论肝硬化腹水患者的血清钠水平与其病情程度具有紧密相关性,监测血清钠的水平可作为判断病情严重程度的重要指标之一,提示在临床上需重视预防、及时发现并治疗低钠血症。
Objective To investigate the relationship between different serum sodium levels and the severity of the disease in cirrhotic patients with ascites. Methods A retrospective analysis of 47 patients with cirrhosis with hyponatremia admitted to our hospital from July 2008 to June 2010 was divided into three groups according to their serum sodium level: light (group A), moderate (group B) Heavy (C group) 3 groups. To compare the relationship between the degree of ascites and the effect of different levels of serum sodium in cirrhotic patients with ascites and the relationship between the degree of hyponatremia and hepatic encephalopathy, hepatorenal syndrome and the incidence of death. Results Compared with group A, the amounts of ascites, hepatic encephalopathy, hepatorenal syndrome and mortality in group B and group C were significantly higher than those in group A (P <0.05), and the effect on treatment was significantly lower (P <0.05) . Conclusions Serum sodium level in patients with cirrhosis and ascites is closely related to the severity of the disease. Monitoring the level of serum sodium can be used as one of the important indicators to judge the severity of the disease. It is suggested that prevention and timely detection and treatment of hyponatremia .