由气脑造影、CT 及 MRI 等检查发现的帕金森病(PD)脑萎缩与神经病理学研究所见的脑萎缩评价不一。PD 的生前诊断常根据其典型的三联征(强直、震颤和运动不能)及对左旋多巴治疗的敏感性。对临床症状不典型的病例,这种药理学诊断标准对 PD 与基底节其它退行性疾病的鉴别诊断十分重要。PD 患者的一些症状不因左旋多巴治疗而改善,故称为与左旋多巴无关症状,可能是因为中枢非多巴胺能神经元系统的进行性病变而引起,并由此导致核磁共振(MRI)检查可见中央萎缩。此外,在一些可引 Cerebral atrophy, found in Parkinson’s disease (PD) brain atrophy and neuropathology studies, as assessed by pneumo-angiography, CT, and MRI, varied. Prenatal diagnosis of PD is often based on its typical triad (rigidity, tremor and motor failure) and its sensitivity to levodopa therapy. For atypical cases of clinical symptoms, this pharmacological diagnostic criteria for the differential diagnosis of PD and basal ganglia other degenerative diseases is very important. Some of the symptoms of PD patients are not improved by treatment with levodopa and are therefore called unrelated symptoms of levodopa which may be due to progressive lesions of the central non-dopaminergic neuron system and thus to nuclear magnetic resonance (MRI) Check the central atrophy can be seen. In addition, some can be cited