食管念珠菌病多发生于长期使用抗生素或激素之后,或在恶性肿瘤、血液病等消耗性疾患的基础上发病。但是,不存在上述条件的人同样可以发生食管念珠菌病。后一类型者自从1964年 Grieve 等报告1例以来,迄今有文献可查者已达5例。本文再报告1例,病人经过6年的随访观察证明,没有任何明显的慢性疾病,也没有长期使用抗生素或激素的历史。食管念珠菌病的主要症状是吞咽困难,咽下疼 Esophageal candidiasis occurs in the long-term use of antibiotics or hormones, or in cancer, blood diseases and other wasting disease based on the disease. However, people without the above conditions can also develop esophageal candidiasis. The latter type has reported 5 cases to date since the report of Grieve et al. In 1964. This article reports another case, the patient after 6 years of follow-up observation showed that there is no obvious chronic disease, there is no long-term history of the use of antibiotics or hormones. Esophageal candidiasis is the main symptoms of dysphagia, swallowing pain