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普遍认为,根据组织学类型制定的分级是提示软组织肉瘤患者预后的重要因素之一。但因软组织肉瘤较少见,组织图像复杂,准确决定其恶性级别是困难的。本文研究各种类型人软组织肉瘤内肥大细胞的数量,以评价其作为预后因素的意义。研究对象共44例,包括成人纤维肉瘤2例,恶性纤维组织细胞瘤11例,脂肪肉瘤5例,横纹肌肉瘤3例,滑膜肉瘤12例,恶性神经鞘瘤3例,其它肉瘤8例。分级情况;Ⅰ级7例,Ⅱ级14例,Ⅲ级23例。切片厚4μm,常规 HE 染色和酸性甲苯胺蓝(pH3.0)染色。甲苯胺蓝清楚地显示出肥大细胞的异染性特
It is generally believed that the grading based on histological type is one of the important factors that suggest the prognosis of patients with soft tissue sarcoma. However, because soft tissue sarcomas are less common and the images of the tissues are complex, it is difficult to accurately determine the malignant grade. This article studies the number of mast cells in various types of human soft tissue sarcoma to evaluate its significance as a prognostic factor. A total of 44 patients were studied, including 2 cases of adult fibrosarcoma, 11 cases of malignant fibrous histocytoma, 5 cases of liposarcoma, 3 cases of rhabdomyosarcoma, 12 cases of synovial sarcoma, 3 cases of malignant schwannoma, and 8 cases of other sarcomas. Graded condition; Grade I in 7 cases, Grade II in 14 cases, Grade III in 23 cases. Slices were 4 μm thick, stained with conventional HE and acid toluidine blue (pH 3.0). Toluidine blue clearly shows the hyperchromaticity of mast cells