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目的 研究小剂量氯化镉对大鼠前列腺基细胞的影响及锌的保护作用。方法 小剂量氯化镉（２ｍｇ／ｋｇ体重）及锌腹腔内注射雄性Ｗｉｓｔａｒ大鼠后４小时到６０天及镉锌联合注射后３天、１５天取材，用透射电镜观察其超微结构改变。结果 镉注射后４小时基细胞与主细胞之间间隙稍有扩大，镉注射后２４小时，基细胞出现较明显的超微结构改变，３天伴有基细胞核的变化１５天基本恢复，６０天基细胞生长活跃，数量较少。结论 镉对大鼠前列腺基细胞有直接损伤作用，锌对镉所致基细胞超微结构改变有一定保护作用。
Objective To study the effect of low dose cadmium chloride on prostatic cells in rats and the protective effect of zinc. Methods Small doses of cadmium chloride (2mg / kg body weight) and intraperitoneal injection of male Wistar rats after 4 hours to 60 days and zinc cadmium and zinc injection 3 days, 15 days after the material was drawn, the ultrastructure was observed by transmission electron microscopy. Results After 4 hours of cadmium injection, the gap between the basal cells and the main cells was slightly enlarged. After 24 hours of cadmium injection, the ultrastructural changes of basal cells appeared obvious. The changes of basal cell nucleus were basically recovered after 3 days and 60 days Basal cell growth is active, the number is less. Conclusions Cadmium has a direct effect on the prostatic cells in rats. Zinc has a protective effect on the ultrastructure of basal cells induced by cadmium.